TNN Antibody (PACO18957)
- SKU:
- PACO18957
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TNN Antibody (PACO18957) |
| Antibody SKU: | PACO18957 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:3000-1:10000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human TNN |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18957(TNN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18957(TNN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
| Synonyms: | tenascin N |
| UniProt Protein Function: | TNN: Involved in neurite outgrowth and cell migration in hippocampal explants. Belongs to the tenascin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Extracellular matrix Chromosomal Location of Human Ortholog: 1q23-q24 Cellular Component: proteinaceous extracellular matrix; cell surface Molecular Function:integrin binding; identical protein binding Biological Process: cell migration; axonogenesis; cell-matrix adhesion; cell growth |
| UniProt Code: | Q9UQP3 |
| NCBI GenInfo Identifier: | 81175198 |
| NCBI Gene ID: | 63923 |
| NCBI Accession: | Q9UQP3.2 |
| UniProt Secondary Accession: | Q9UQP3,Q5R360, B9EGP3, |
| UniProt Related Accession: | Q9UQP3 |
| Molecular Weight: | 144,034 Da |
| NCBI Full Name: | Tenascin-N |
| NCBI Synonym Full Names: | tenascin N |
| NCBI Official Symbol: | TNN |
| NCBI Official Synonym Symbols: | TN-W |
| NCBI Protein Information: | tenascin-N; TN-N |
| UniProt Protein Name: | Tenascin-N |
| Protein Family: | Tenascin |
| UniProt Gene Name: | TNN |
| UniProt Entry Name: | TENN_HUMAN |
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