TNF RII/TNFRSF1B/CD120b Polyclonal Antibody
- SKU:
- CAB24513
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TNF RII/TNFRSF1B/CD120b Polyclonal Antibody |
| Product Code: | CAB24513 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | L929 |
| Cellular Location: | Secreted and Cell membrane |
Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 23-258 of mouse TNF RII/TNFRSF1B/CD120b(NP_035740.2). |
| Sequence: | VPAQV VLTPY KPEPG YECQI SQEYY DRKAQ MCCAK CPPGQ YVKHF CNKTS DTVCA DCEAS MYTQV WNQFR TCLSC SSSCT TDQVE IRACT KQQNR VCACE AGRYC ALKTH SGSCR QCMRL SKCGP GFGVA SSRAP NGNVL CKACA PGTFS DTTSS TDVCR PHRIC SILAI PGNAS TDAVC APESP TLSAI PRTLY VSQPE PTRSQ PLDQE PGPSQ TPSIL TSLGS TPIIE QSTKG G |
| Synonyms: | p75, TNFBR, Tnfr2, CD120b, TNF-R2, TNFR80, TNFRII, Tnfr-1, TNF-R75, TNF-R-II, TNF-alphaR2, TNFalpha-R2 |
| Calculated MW: | 50kDa |
| Observed MW: | 50kDa |
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