Description
system_update_alt Datasheet
Product Name: | TNF a Antibody |
Product Sku: | CPAB0031 |
Size: | 500μg |
Host Species: | Mouse |
Immunogen: | r.Human TNF-a |
Clone: | NYRhTNFa-E2. |
Reactivity: | Human |
Applications: | Immuneprecipitation, Western Blot, ELISA |
Purification Method: | Ion exchange |
Isotype: | IgG1 |
Background: | Tumor necrosis factor is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesisand viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer. |
Synonyms: | TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2. |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |