Tmprss15 Antibody (PACO51878)
- SKU:
- PACO51878
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Tmprss15 Antibody (PACO51878) |
| Antibody SKU: | PACO51878 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mouse, Human, Rat |
| Immunogen: | Recombinant Mouse Enteropeptidase protein (830-1069AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: HepG2 whole cell lysate, Rat liver tissue. All lanes: Tmprss15 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 119 kDa. Observed band size: 119 kDa.. |
| Background: | Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases (By similarity). |
| Synonyms: | Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain], Tmprss15, Entk Prss7 |
| UniProt Protein Function: | PRSS7: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD); a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive. Belongs to the peptidase S1 family.Protein type: Protease; EC 3.4.21.9; Membrane protein, integralCellular Component: integral to membrane; membraneMolecular Function: hydrolase activity; peptidase activity; scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activityBiological Process: proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P97435 |
| NCBI GenInfo Identifier: | 6679489 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_032967.1 |
| UniProt Secondary Accession: | P97435 |
| UniProt Related Accession: | P97435 |
| Molecular Weight: | Predicted Molecular Mass: 22.6kDaAccurate Molecular Mass: 25kDa |
| NCBI Full Name: | enteropeptidase isoform 1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Enteropeptidase |
| UniProt Synonym Protein Names: | Enterokinase; Serine protease 7; Transmembrane protease serine 15 |
| Protein Family: | |
| UniProt Gene Name: | Tmprss15 |
| UniProt Entry Name: | ENTK_MOUSE |
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