TMIGD2 Antibody (PACO50894)
- SKU:
- PACO50894
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMIGD2 Antibody (PACO50894) |
| Antibody SKU: | PACO50894 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO50894 at dilution of 1:100. |
 | Immunofluorescent analysis of PC-3 cells using PACO50894 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
| Synonyms: | Transmembrane and immunoglobulin domain-containing protein 2 (CD28 homolog) (Immunoglobulin and proline-rich receptor 1) (IGPR-1), TMIGD2, CD28H IGPR1 |
| UniProt Protein Function: | IGPR-1: Plays a role in cell-cell interaction, cell migration, and angiogenesis. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: integral to membrane; plasma membraneMolecular Function: protein binding; coreceptor activityBiological Process: positive regulation of cytokine production; T cell costimulation; signal transduction; positive regulation of activated T cell proliferation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96BF3 |
| NCBI GenInfo Identifier: | 281306838 |
| NCBI Gene ID: | 126259 |
| NCBI Accession: | NP_653216.2 |
| UniProt Secondary Accession: | Q96BF3,Q6UW59 |
| UniProt Related Accession: | Q96BF3 |
| Molecular Weight: | 30,319 Da |
| NCBI Full Name: | transmembrane and immunoglobulin domain-containing protein 2 isoform 1 |
| NCBI Synonym Full Names: | transmembrane and immunoglobulin domain containing 2 |
| NCBI Official Symbol: | TMIGD2 |
| NCBI Official Synonym Symbols: | CD28H; IGPR1; IGPR-1 |
| NCBI Protein Information: | transmembrane and immunoglobulin domain-containing protein 2 |
| UniProt Protein Name: | Transmembrane and immunoglobulin domain-containing protein 2 |
| UniProt Synonym Protein Names: | CD28 homolog; Immunoglobulin and proline-rich receptor 1; IGPR-1 |
| Protein Family: | Transmembrane and immunoglobulin domain-containing protein |
| UniProt Gene Name: | TMIGD2 |
| UniProt Entry Name: | TMIG2_HUMAN |
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