TMEM8B Antibody (PACO18753)
- SKU:
- PACO18753
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMEM8B Antibody (PACO18753) |
| Antibody SKU: | PACO18753 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human TMEM8B |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18753(TMEM8B Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18753(TMEM8B Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. |
| Synonyms: | Transmembrane protein 8B |
| UniProt Protein Function: | TMEM8B: May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. Belongs to the TMEM8 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 9p13.3Cellular Component: cell surface; mitochondrion; endoplasmic reticulum; integral to membrane; plasma membrane; nucleusMolecular Function: protein bindingBiological Process: cell-matrix adhesion; regulation of growth; regulation of mitotic cell cycle |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A6NDV4 |
| NCBI GenInfo Identifier: | 189029214 |
| NCBI Gene ID: | 51754 |
| NCBI Accession: | A6NDV4.2 |
| UniProt Secondary Accession: | A6NDV4,O75539, Q49AB1, Q4KMX5, Q5TCW5, Q9HBY2, Q9P0U7 B3KQF3 |
| UniProt Related Accession: | A6NDV4 |
| Molecular Weight: | 28,336 Da |
| NCBI Full Name: | Transmembrane protein 8B |
| NCBI Synonym Full Names: | transmembrane protein 8B |
| NCBI Official Symbol: | TMEM8B |
| NCBI Official Synonym Symbols: | NGX6; NAG-5; C9orf127 |
| NCBI Protein Information: | transmembrane protein 8B; Protein NGX6; nasopharyngeal carcinoma expressed 6; nasopharyngeal carcinoma related protein; nasopharyngeal carcinoma-associated gene 6 protein; protein NAG-5 |
| UniProt Protein Name: | Transmembrane protein 8B |
| UniProt Synonym Protein Names: | Nasopharyngeal carcinoma-associated gene 6 protein; Protein NAG-5; Protein NGX6 |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM8B |
| UniProt Entry Name: | TMM8B_HUMAN |
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