TMEM88 Antibody (PACO59920)
- SKU:
- PACO59920
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMEM88 Antibody (PACO59920) |
| Antibody SKU: | PACO59920 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transmembrane protein 88 protein (109-159AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of A549 cells with PACO59920 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardiomyocyte development. |
| Synonyms: | Transmembrane protein 88, TMEM88, TMEM88A |
| UniProt Protein Function: | TMEM88: Belongs to the TMEM88 family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 17p13.1Cellular Component: plasma membrane; integral to membraneBiological Process: Wnt receptor signaling pathway; multicellular organismal development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6PEY1 |
| NCBI GenInfo Identifier: | 44662813 |
| NCBI Gene ID: | 92162 |
| NCBI Accession: | NP_981956.1 |
| UniProt Secondary Accession: | Q6PEY1 |
| UniProt Related Accession: | Q6PEY1 |
| Molecular Weight: | 17,251 Da |
| NCBI Full Name: | transmembrane protein 88 |
| NCBI Synonym Full Names: | transmembrane protein 88 |
| NCBI Official Symbol: | TMEM88 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | transmembrane protein 88 |
| UniProt Protein Name: | Transmembrane protein 88 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM88 |
| UniProt Entry Name: | TMM88_HUMAN |
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