Description
Antibody Name: | TMEM59L Antibody (PACO30626) |
Antibody SKU: | PACO30626 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Transmembrane protein 59-like protein (27-267AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: TMEM59L antibody at 3µg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 38 kDa Observed band size: 38 kDa . | |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO30626 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO30626 at dilution of 1:100. |
Background: | Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. |
Synonyms: | Transmembrane protein 59-like (Brain-specific membrane-anchored protein), TMEM59L, BSMAP C19orf4 |
UniProt Protein Function: | TMEM59L: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.Protein type: Membrane protein, integralChromosomal Location of Human Ortholog: 19p12Cellular Component: Golgi membrane; membrane; integral to membrane |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UK28 |
NCBI GenInfo Identifier: | 6912274 |
NCBI Gene ID: | 25789 |
NCBI Accession: | NP_036241 |
UniProt Secondary Accession: | Q9UK28 |
UniProt Related Accession: | Q9UK28 |
Molecular Weight: | |
NCBI Full Name: | transmembrane protein 59-like |
NCBI Synonym Full Names: | transmembrane protein 59 like |
NCBI Official Symbol: | TMEM59L |
NCBI Official Synonym Symbols: | BSMAP; C19orf4 |
NCBI Protein Information: | transmembrane protein 59-like |
UniProt Protein Name: | Transmembrane protein 59-like |
UniProt Synonym Protein Names: | Brain-specific membrane-anchored protein |
Protein Family: | Transmembrane protein |
UniProt Gene Name: | TMEM59L |
UniProt Entry Name: | TM59L_HUMAN |