Description
| Antibody Name: | TMEM38B Antibody (PACO41438) |
| Antibody SKU: | PACO41438 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Trimeric intracellular cation channel type B protein (249-291AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: TMEM38B antibody at 1.5µg/ml. Lane 1: Mouse thymus tissue. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 33 kDa. Observed band size: 33 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO41438 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO41438 at dilution of 1:100. |
| Background: | Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). |
| Synonyms: | Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B), TMEM38B, C9orf87 |
| UniProt Protein Function: | TMEM38B: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Belongs to the TMEM38 family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 9q31.2Cellular Component: integral to membrane; nuclear membrane; nucleus; sarcoplasmic reticulum membraneMolecular Function: potassium channel activityDisease: Osteogenesis Imperfecta, Type Xiv |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes an intracellular monovalent cation channel that functions in maintenance of intracellular calcium release. Mutations in this gene may be associated with autosomal recessive osteogenesis. [provided by RefSeq, Oct 2012] |
| UniProt Code: | Q9NVV0 |
| NCBI GenInfo Identifier: | 8922461 |
| NCBI Gene ID: | 55151 |
| NCBI Accession: | NP_060582.1 |
| UniProt Secondary Accession: | Q9NVV0,Q5JR63, Q5SVN5, Q5SVN6, Q5VTE2, Q6IA97 |
| UniProt Related Accession: | Q9NVV0 |
| Molecular Weight: | 32,510 Da |
| NCBI Full Name: | trimeric intracellular cation channel type B |
| NCBI Synonym Full Names: | transmembrane protein 38B |
| NCBI Official Symbol: | TMEM38B |
| NCBI Official Synonym Symbols: | OI14; TRICB; TRIC-B; C9orf87; D4Ertd89e; bA219P18.1 |
| NCBI Protein Information: | trimeric intracellular cation channel type B |
| UniProt Protein Name: | Trimeric intracellular cation channel type B |
| UniProt Synonym Protein Names: | Transmembrane protein 38B |
| Protein Family: | Trimeric intracellular cation channel |
| UniProt Gene Name: | TMEM38B |
| UniProt Entry Name: | TM38B_HUMAN |


