Description
Antibody Name: | TMEM38B Antibody (PACO41438) |
Antibody SKU: | PACO41438 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Trimeric intracellular cation channel type B protein (249-291AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: TMEM38B antibody at 1.5µg/ml. Lane 1: Mouse thymus tissue. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 33 kDa. Observed band size: 33 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO41438 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO41438 at dilution of 1:100. |
Background: | Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). |
Synonyms: | Trimeric intracellular cation channel type B (TRIC-B) (TRICB) (Transmembrane protein 38B), TMEM38B, C9orf87 |
UniProt Protein Function: | TMEM38B: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Belongs to the TMEM38 family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 9q31.2Cellular Component: integral to membrane; nuclear membrane; nucleus; sarcoplasmic reticulum membraneMolecular Function: potassium channel activityDisease: Osteogenesis Imperfecta, Type Xiv |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes an intracellular monovalent cation channel that functions in maintenance of intracellular calcium release. Mutations in this gene may be associated with autosomal recessive osteogenesis. [provided by RefSeq, Oct 2012] |
UniProt Code: | Q9NVV0 |
NCBI GenInfo Identifier: | 8922461 |
NCBI Gene ID: | 55151 |
NCBI Accession: | NP_060582.1 |
UniProt Secondary Accession: | Q9NVV0,Q5JR63, Q5SVN5, Q5SVN6, Q5VTE2, Q6IA97 |
UniProt Related Accession: | Q9NVV0 |
Molecular Weight: | 32,510 Da |
NCBI Full Name: | trimeric intracellular cation channel type B |
NCBI Synonym Full Names: | transmembrane protein 38B |
NCBI Official Symbol: | TMEM38B |
NCBI Official Synonym Symbols: | OI14; TRICB; TRIC-B; C9orf87; D4Ertd89e; bA219P18.1 |
NCBI Protein Information: | trimeric intracellular cation channel type B |
UniProt Protein Name: | Trimeric intracellular cation channel type B |
UniProt Synonym Protein Names: | Transmembrane protein 38B |
Protein Family: | Trimeric intracellular cation channel |
UniProt Gene Name: | TMEM38B |
UniProt Entry Name: | TM38B_HUMAN |