TMEM214 Antibody (PACO62719)
- SKU:
- PACO62719
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IP
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMEM214 Antibody (PACO62719) |
| Antibody SKU: | PACO62719 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IP |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IP:1:200-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transmembrane protein 214 protein (2-236AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: K562 whole cell lysate, HepG2 whole cell lysate, HL-60 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate. All lanes: TMEM214 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 78, 73 kDa. Observed band size: 78 kDa. |
 | Immunoprecipitating TMEM214 in HepG2 whole cell lysate. Lane 1: Rabbit control IgG instead of PACO62719 in HepG2 whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/50000). Lane 2: PACO62719 (5µg) + HepG2 whole cell lysate (0.5mg). Lane 3: HepG2 whole cell lysate (20µg). |
| Background: | Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress. |
| Synonyms: | Transmembrane protein 214, TMEM214 |
| UniProt Protein Function: | TMEM214: Belongs to the TMEM214 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2p23.3Cellular Component: cytoplasm; cytoplasmic microtubule; endoplasmic reticulum; Golgi apparatus |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6NUQ4 |
| NCBI GenInfo Identifier: | 46250002 |
| NCBI Gene ID: | 54867 |
| NCBI Accession: | BC068479 |
| UniProt Secondary Accession: | Q6NUQ4,Q53SW1, Q69YH4, Q8NC45, Q8WZ37, Q9NXH2, A6NNF2 B3KUI9, B5MCD8, D6W547 |
| UniProt Related Accession: | Q6NUQ4 |
| Molecular Weight: | 72,040 Da |
| NCBI Full Name: | Homo sapiens transmembrane protein 214, mRNA |
| NCBI Synonym Full Names: | transmembrane protein 214 |
| NCBI Official Symbol: | TMEM214 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | transmembrane protein 214 |
| UniProt Protein Name: | Transmembrane protein 214 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM214 |
| UniProt Entry Name: | TM214_HUMAN |
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