TMEM150A Antibody (PACO60192)
- SKU:
- PACO60192
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMEM150A Antibody (PACO60192) |
| Antibody SKU: | PACO60192 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transmembrane protein 150A protein (24-75AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO60192 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex. Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. May also play a role in fasting-induced catabolism (By similarity). |
| Synonyms: | Transmembrane protein 150A (Transmembrane protein 150), TMEM150A, TMEM150 |
| UniProt Protein Function: | TMEM150A: Possible role in fasting-induced catabolism. Belongs to the DRAM/TMEM150 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2p11.2Cellular Component: integral to plasma membrane; lysosomeMolecular Function: protein bindingBiological Process: phosphoinositide phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86TG1 |
| NCBI GenInfo Identifier: | 74727425 |
| NCBI Gene ID: | 129303 |
| NCBI Accession: | Q86TG1.1 |
| UniProt Secondary Accession: | Q86TG1,Q8N2R6, A8K764, B7WPQ9, D6W5L2 |
| UniProt Related Accession: | Q86TG1 |
| Molecular Weight: | 23,035 Da |
| NCBI Full Name: | Transmembrane protein 150A |
| NCBI Synonym Full Names: | transmembrane protein 150A |
| NCBI Official Symbol: | TMEM150A |
| NCBI Official Synonym Symbols: | TM6P1; TMEM150 |
| NCBI Protein Information: | transmembrane protein 150A |
| UniProt Protein Name: | Transmembrane protein 150A |
| UniProt Synonym Protein Names: | Transmembrane protein 150 |
| Protein Family: | Transmembrane protein |
| UniProt Gene Name: | TMEM150A |
| UniProt Entry Name: | T150A_HUMAN |
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