Description
| Antibody Name: | TMEM131L Antibody (PACO63663) |
| Antibody SKU: | PACO63663 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Transmembrane protein 131-like protein (963-978AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of U251 cells with PACO63663 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation. |
| Synonyms: | Transmembrane protein 131-like, TMEM131L, KIAA0922 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A2VDJ0 |
| NCBI GenInfo Identifier: | 187608809 |
| NCBI Gene ID: | 23240 |
| NCBI Accession: | NP_056011 |
| UniProt Secondary Accession: | A2VDJ0,Q7LGA7, Q86Y92, Q8WU56, Q9H065, Q9Y2D7, B3KRV3 D3DP10 |
| UniProt Related Accession: | A2VDJ0 |
| Molecular Weight: | 163,518 Da |
| NCBI Full Name: | transmembrane protein 131-like isoform 2 |
| NCBI Synonym Full Names: | KIAA0922 |
| NCBI Official Symbol: | KIAA0922 |
| NCBI Official Synonym Symbols: | TMEM131L |
| NCBI Protein Information: | transmembrane protein 131-like |
| UniProt Protein Name: | Transmembrane protein 131-like |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | KIAA0922 |
| UniProt Entry Name: | T131L_HUMAN |
