Description
system_update_alt Datasheet
Product Name: | TMEFF2 Antibody |
Product Sku: | CPAB0559 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human TMEFF2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TMEFF2 amino acids 41-15 purified from Ecoli. |
Clone: | PJ4B6AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Immunohistochemistry |
Purification Method: | TMEFF2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | TMEFF2 is a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factorlike domain. TMEFF2 has limited normal tissue distribution and is highly overexpressed in prostate cancer. The shedded form of TMEFF2 up-regulates cancer cell proliferation, most likely by promoting ERK1/2 phosphorylation. TMEFF2 is down-regulated in tumor cell lines in response to a high level of methylation in the 5'' region. |
Synonyms: | TMEFF2, Tomoregulin-2, Transmembrane protein with EGF-like and two follistatin-like domains, Hyperplastic polyposis protein 1, HPP1, TENB2, TPEF, TR, CT120.2. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |