TMED4 Antibody (PACO17272)
- SKU:
- PACO17272
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TMED4 Antibody (PACO17272) |
| Antibody SKU: | PACO17272 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human TMED4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17272(TMED4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE,Lysate: 40 μg,Lane 1-5: HepG2 cells, K562 cells, Hela cells, A549 cells, Mouse intestines tissue,Primary antibody: PACO17272(TMED4 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17272(TMED4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity). |
| Synonyms: | transmembrane emp24 protein transport domain containing 4 |
| UniProt Protein Function: | TMED4: Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis. Belongs to the EMP24/GP25L family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 7p13 Molecular Function:signal transducer activity Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade |
| UniProt Code: | Q7Z7H5 |
| NCBI GenInfo Identifier: | 62287892 |
| NCBI Gene ID: | 222068 |
| NCBI Accession: | Q7Z7H5.1 |
| UniProt Secondary Accession: | Q7Z7H5,Q56VW3, Q7Z432, Q8N2P6, A4D2K8, B4DFJ4, |
| UniProt Related Accession: | Q7Z7H5 |
| Molecular Weight: | 20,781 Da |
| NCBI Full Name: | Transmembrane emp24 domain-containing protein 4 |
| NCBI Synonym Full Names: | transmembrane p24 trafficking protein 4 |
| NCBI Official Symbol: | TMED4 |
| NCBI Official Synonym Symbols: | HNLF; ERS25; p24a3; GMP25iso; p24alpha3 |
| NCBI Protein Information: | transmembrane emp24 domain-containing protein 4 |
| UniProt Protein Name: | Transmembrane emp24 domain-containing protein 4 |
| UniProt Synonym Protein Names: | Endoplasmic reticulum stress-response protein 25; ERS25; GMP25iso; Putative NF-kappa-B-activating protein 156; p24 family protein alpha-3; p24alpha3 |
| Protein Family: | Transmembrane emp24 domain-containing protein |
| UniProt Gene Name: | TMED4 |
| UniProt Entry Name: | TMED4_HUMAN |
| Antibodies |
| TMED4 Antibody (PACO12789) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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