TLR13 Antibody (PACO03217)
- SKU:
- PACO03217
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TLR13 Antibody |
| Antibody SKU: | PACO03217 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | IHC:1:200-1:500 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Protein |
| Form: | Liquid |
| Storage Buffer: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Purification Method: | Affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Toll-like receptor 13 |
| UniProt Protein Function: | TLR13: Component of innate and adaptive immunity that recognizes and binds 23S rRNA from bacteria. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Specifically binds the 5'-CGGAAAGACC-3' sequence on bacterial 23S rRNA, a sequence also bound by MLS group antibiotics (including erythromycin). May also recognize vesicular stomatitis virus; however, these data require additional evidences. Belongs to the Toll-like receptor family.Protein type: Membrane protein, integral; Receptor, misc.Cellular Component: cytoplasm; endosome; integral to membrane; membraneMolecular Function: double-stranded RNA binding; protein binding; protein homodimerization activity; RNA binding; rRNA bindingBiological Process: immune system process; inflammatory response; innate immune response; MyD88-dependent toll-like receptor signaling pathway; regulation of MAPKKK cascade; response to virus; signal transduction; toll-like receptor 13 signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6R5N8 |
| NCBI GenInfo Identifier: | 109734930 |
| NCBI Gene ID: | 279572 |
| NCBI Accession: | AAI17914.1 |
| UniProt Secondary Accession: | Q6R5N8,Q148Y7, Q3TDS2 |
| UniProt Related Accession: | Q6R5N8 |
| Molecular Weight: | 114,443 Da |
| NCBI Full Name: | Toll-like receptor 13 |
| NCBI Synonym Full Names: | toll-like receptor 13 |
| NCBI Official Symbol: | Tlr13 |
| NCBI Official Synonym Symbols: | Gm713; AI666735 |
| NCBI Protein Information: | toll-like receptor 13 |
| UniProt Protein Name: | Toll-like receptor 13 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Toll-like receptor |
| UniProt Gene Name: | Tlr13 |
| UniProt Entry Name: | TLR13_MOUSE |
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