Description
Product Name: | TLK1 Polyclonal Antibody |
Product Code: | CAB21987 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, Jurkat, NIH/3T3 |
Cellular Location: | Nucleus |
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TLK1 (NP_036422.3). |
Sequence: | FEYQG GNGSS PVRGI PPAIR SPQNS HSHST PSSSV RPNSP SPTAL AFGDH PIVQP KQLSF KIIQT DLTML KLAAL ESNKI QDLEK KEGRI DDLLR ANCDL R |
Synonyms: | PKU-beta |
Calculated MW: | 87kDa |
Observed MW: | 87kDa |