Description
Antibody Name: | TKTL2 Antibody (PACO41050) |
Antibody SKU: | PACO41050 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Transketolase-like protein 2 protein (1-300AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO41050 at dilution of 1:100. |
Background: | Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. |
Synonyms: | Transketolase-like protein 2 (EC 2.2.1.1), TKTL2 |
UniProt Protein Function: | TKTL2: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. Belongs to the transketolase family.Protein type: Transferase; Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1Chromosomal Location of Human Ortholog: 4q32.2Cellular Component: cytoplasm |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9H0I9 |
NCBI GenInfo Identifier: | 74717985 |
NCBI Gene ID: | 84076 |
NCBI Accession: | Q9H0I9.1 |
UniProt Secondary Accession: | Q9H0I9,Q8NCT0, Q96M82, A4FVB4 |
UniProt Related Accession: | Q9H0I9 |
Molecular Weight: | 67,877 Da |
NCBI Full Name: | Transketolase-like protein 2 |
NCBI Synonym Full Names: | transketolase like 2 |
NCBI Official Symbol: | TKTL2 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | transketolase-like protein 2 |
UniProt Protein Name: | Transketolase-like protein 2 |
UniProt Synonym Protein Names: | |
Protein Family: | Transketolase-like protein |
UniProt Gene Name: | TKTL2 |
UniProt Entry Name: | TKTL2_HUMAN |