Description
| Antibody Name: | TKTL2 Antibody (PACO41050) |
| Antibody SKU: | PACO41050 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transketolase-like protein 2 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO41050 at dilution of 1:100. |
| Background: | Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. |
| Synonyms: | Transketolase-like protein 2 (EC 2.2.1.1), TKTL2 |
| UniProt Protein Function: | TKTL2: Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. Belongs to the transketolase family.Protein type: Transferase; Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.1Chromosomal Location of Human Ortholog: 4q32.2Cellular Component: cytoplasm |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H0I9 |
| NCBI GenInfo Identifier: | 74717985 |
| NCBI Gene ID: | 84076 |
| NCBI Accession: | Q9H0I9.1 |
| UniProt Secondary Accession: | Q9H0I9,Q8NCT0, Q96M82, A4FVB4 |
| UniProt Related Accession: | Q9H0I9 |
| Molecular Weight: | 67,877 Da |
| NCBI Full Name: | Transketolase-like protein 2 |
| NCBI Synonym Full Names: | transketolase like 2 |
| NCBI Official Symbol: | TKTL2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | transketolase-like protein 2 |
| UniProt Protein Name: | Transketolase-like protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transketolase-like protein |
| UniProt Gene Name: | TKTL2 |
| UniProt Entry Name: | TKTL2_HUMAN |
