Name: Thrsp Antibody (PACO46610)
SKU: PACO46610
Availability: OutOfStock

Antibody Name:	Thrsp Antibody (PACO46610)
Antibody SKU:	PACO46610
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse Thyroid hormone-inducible hepatic protein (1-150AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunofluorescent analysis of MCF-7 cells using PACO46610 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:	Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid, chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB (By similarity).
Synonyms:	Thyroid hormone-inducible hepatic protein (Spot 14 protein) (S14) (SPOT14), Thrsp, S14

UniProt Protein Function:	THRSP: Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. Belongs to the SPOT14 family.Protein type: Unknown functionCellular Component: nucleoplasm; cytoplasm; nucleus; cytosolMolecular Function: protein binding; protein homodimerization activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; lipid metabolic process; regulation of lipid biosynthetic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q62264
NCBI GenInfo Identifier:	6678345
NCBI Gene ID:	21835
NCBI Accession:	NP_033407.1
UniProt Secondary Accession:	Q62264
UniProt Related Accession:	Q62264
Molecular Weight:	17,093 Da
NCBI Full Name:	thyroid hormone-inducible hepatic protein
NCBI Synonym Full Names:	thyroid hormone responsive
NCBI Official Symbol:	Thrsp
NCBI Official Synonym Symbols:	S14
NCBI Protein Information:	thyroid hormone-inducible hepatic protein; SPOT14; spot 14 protein; thyroid hormone responsive SPOT14 homolog
UniProt Protein Name:	Thyroid hormone-inducible hepatic protein
UniProt Synonym Protein Names:	Spot 14 protein; S14; SPOT14
Protein Family:	Thyroid hormone-inducible hepatic protein
UniProt Gene Name:	Thrsp
UniProt Entry Name:	THRSP_MOUSE