THAP9 Antibody (PACO20677)
- SKU:
- PACO20677
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | THAP9 Antibody (PACO20677) |
| Antibody SKU: | PACO20677 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human THAP9 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20677(THAP9 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | THAP9 (THAP domain-containing protein 9) is a 903 amino acid, protein that contains one THAP-type zinc finger. The gene that encodes THAP9 contains roughly 19,448 bases and maps to human chromosome 4q21.22. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acid, mia and polycystic kidney disease. |
| Synonyms: | THAP domain containing 9 |
| UniProt Protein Function: | THAP9: Active transposase that specifically recognizes the bipartite 5'-TXXGGGX(A/T)-3' consensus motif and mediates transpositionChromosomal Location of Human Ortholog: 4q21.22Molecular Function: transferase activity; sequence-specific DNA binding; metal ion binding; transposase activityBiological Process: DNA integration; transposition, DNA-mediated; DNA recombination |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H5L6 |
| NCBI GenInfo Identifier: | 94536788 |
| NCBI Gene ID: | 79725 |
| NCBI Accession: | NP_078948.3 |
| UniProt Secondary Accession: | Q9H5L6,Q59AC9, B3KRE2 |
| UniProt Related Accession: | Q9H5L6 |
| Molecular Weight: | 103,411 Da |
| NCBI Full Name: | DNA transposase THAP9 |
| NCBI Synonym Full Names: | THAP domain containing 9 |
| NCBI Official Symbol: | THAP9 |
| NCBI Official Synonym Symbols: | hTh9 |
| NCBI Protein Information: | DNA transposase THAP9; THAP domain-containing protein 9 |
| UniProt Protein Name: | DNA transposase THAP9 |
| UniProt Synonym Protein Names: | THAP domain-containing protein 9; hTh9 |
| Protein Family: | DNA transposase |
| UniProt Gene Name: | THAP9 |
| UniProt Entry Name: | THAP9_HUMAN |
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