TGM3 Polyclonal Antibody
- SKU:
- CAB24495
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | TGM3 Polyclonal Antibody |
| Product Code: | CAB24495 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, 293T-TGM35-His(C) |
| Cellular Location: | cytoplasm, extracellular exosome |
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human TGM3 (NP_003236.3). |
| Sequence: | SRVIT NFNSA HDTDR NLSVD VYYDP MGNPL DKGSD SVWNF HVWNE GWFVR SDLGP SYGGW QVLDA TPQER SQGVF QCGPA SVIGV REGDV QLNFD MPFIF AEVNA DRITW LYDNT TGKQW KNSVN SHTIG RYIST KAVGS NARMD VTDKY KYPEG SDQER QVFQK ALGKL KPNTP FAATS SMGLE TEEQE |
| Synonyms: | TGM3, TGE, UHS2, transglutaminase 3 |
| Calculated MW: | 76kDa |
| Observed MW: | 70kDa |
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