Antibody Name:	TGFB1 Antibody (PACO30347)
Antibody SKU:	PACO30347
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Chicken
Immunogen:	Recombinant Chicken Transforming growth factor beta-1 proprotein protein (260-373AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:

Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity).

Synonyms:

Transforming growth factor beta-1 proprotein (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)] (Transforming growth factor beta-1), TGFB1

UniProt Protein Function:	Multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Mediates SMAD2/3 activation by inducing its phosphorylation and subsequent translocation to the nucleus ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:	P09531
NCBI GenInfo Identifier:	1729918
NCBI Gene ID:	100873157
NCBI Accession:	P09531.2
UniProt Secondary Accession:	P09531
UniProt Related Accession:	P09531
Molecular Weight:
NCBI Full Name:	Transforming growth factor beta-1
NCBI Synonym Full Names:	transforming growth factor beta 1
NCBI Official Symbol:	TGFB1
NCBI Official Synonym Symbols:	TGFB4; TGF-beta4
NCBI Protein Information:	transforming growth factor beta-1; LOW QUALITY PROTEIN: transforming growth factor beta-1
UniProt Protein Name:	Transforming growth factor beta-1
UniProt Synonym Protein Names:
Protein Family:	Transforming growth factor
UniProt Gene Name:	TGFB1
UniProt Entry Name: