TGF beta Receptor I (TGFBR1) Monoclonal Antibody
- SKU:
- CAB22151
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TGF beta Receptor I (TGFBR1) Monoclonal Antibody |
| Product Code: | CAB22151 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55592 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | SK-BR-3, U-87MG |
| Cellular Location: | Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TGF beta Receptor I (TGFBR1) (NP_004603.1). |
| Sequence: | CCNQD HCNKI ELPTT VKSSP GLGPV ELAAV IAGPV CFVCI SLMLM VYICH NRTVI HHRVP NEEDP SLDRP FISEG TTLKD LIYDM TTSGS GSGLP LLVQR T |
| Synonyms: | AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, TBRI, ALK-5, LDS1A, LDS2A, TBR-i, TGFR-1, ACVRLK4, tbetaR-I |
| Calculated MW: | 56kDa |
| Observed MW: | 56kDa |
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