Description
Product Name: | TFF1/pS2 Monoclonal Antibody |
Product Code: | CAB22999 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59782 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, IP, ELISA |
Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | MCF7, Mouse stomach, Rat stomach |
Cellular Location: | extracellular region, extracellular space |
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Immunogen: | A synthesized peptide derived from human TFF1/pS2. |
Sequence: | MATME NKVIC ALVLV SMLAL GTLAE AQTET CTVAP RERQN CGFPG VTPSQ CANKG CCFDD TVRGV PWCFY PNTID VPPEE ECEF |
Synonyms: | pS2, BCEI, HPS2, HP1.A, pNR-2, D21S21 |
Calculated MW: | 9kDa |
Observed MW: | 13kDa |