Description
Product Name: | TFEB Polyclonal Antibody |
Product Code: | CAB21657 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence, Immunohistochemistry |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Positive Samples: | Mouse liver, Mouse heart |
Cellular Location: | cytoplasm, cytosol, extracellular exosome, microtubule cytoskeleton, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial matrix, mitochondrial nucleoid, mitochondrion, nucleus |
Enables DNA-binding transcription factor activity; enzyme binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to amino acid starvation; lysosome localization; and positive regulation of autophagy. Located in cytosol; lysosomal membrane; and nucleoplasm.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 391-461 of human TFEB (NP_009093.1). |
Sequence: | FHHLD FSHSL SFGGR EDEGP PGYPE PLAPG HGSPF PSLSK KDLDL MLLDD SLLPL ASDPL LSTMS PEASK A |
Synonyms: | TCFEB, BHLHE35, ALPHATFEB |
Calculated MW: | 52kDa |
Observed MW: | 65-70kDa |