TFDP3 Antibody (PACO53474)
- SKU:
- PACO53474
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TFDP3 Antibody (PACO53474) |
| Antibody SKU: | PACO53474 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transcription factor Dp family member 3 protein (61-196AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO53474 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO53474 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase. |
| Synonyms: | Transcription factor Dp family member 3 (Cancer/testis antigen 30) (CT30) (Hepatocellular carcinoma-associated antigen 661), TFDP3, DP4 HCA661 |
| UniProt Protein Function: | TFDP3: Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase. Belongs to the E2F/DP family.Protein type: DNA-binding; Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq26.2Cellular Component: cytoplasm; nucleusMolecular Function: protein heterodimerization activityBiological Process: G1/S transition of mitotic cell cycle; regulation of transcription from RNA polymerase II promoter; response to DNA damage stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.[provided by RefSeq, May 2010] |
| UniProt Code: | Q5H9I0 |
| NCBI GenInfo Identifier: | 74762180 |
| NCBI Gene ID: | 51270 |
| NCBI Accession: | Q5H9I0.1 |
| UniProt Secondary Accession: | Q5H9I0,Q6DK49, Q9NZ54 |
| UniProt Related Accession: | Q5H9I0 |
| Molecular Weight: | 44,967 Da |
| NCBI Full Name: | Transcription factor Dp family member 3 |
| NCBI Synonym Full Names: | transcription factor Dp family member 3 |
| NCBI Official Symbol: | TFDP3 |
| NCBI Official Synonym Symbols: | DP4; CT30; HCA661 |
| NCBI Protein Information: | transcription factor Dp family member 3 |
| UniProt Protein Name: | Transcription factor Dp family member 3 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 30; CT30; Hepatocellular carcinoma-associated antigen 661 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | TFDP3 |
| UniProt Entry Name: | TFDP3_HUMAN |
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