Antibody Name:	Tf Antibody (PACO25536)
Antibody SKU:	PACO25536
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:	Rat
Immunogen:	Rat Transferrin (Native Protein)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot
All lanes: Rat Transferrin antibody at 2µg/ml
Lane 1: Rat Transferrin at 0.2 mg
Lane 2: Rat Transferrin at 0.1 mg
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 77, 55 kDa
Observed band size: 77 kDa
.

Background:

Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions.

Synonyms:

Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Liver regeneration-related protein LRRG03) (Siderophilin), Tf

UniProt Protein Function:	Transferrins are iron binding transport proteins which can bind two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
NCBI Summary:	plays a role iin iron transport and homeostasis [RGD, Feb 2006]
UniProt Code:	P12346
NCBI GenInfo Identifier:	61556986
NCBI Gene ID:	24825
NCBI Accession:	NP_001013128.1
UniProt Secondary Accession:	P12346,Q63602, Q64628, Q64630, Q7TNX0,
UniProt Related Accession:	P12346
Molecular Weight:	76
NCBI Full Name:	serotransferrin
NCBI Synonym Full Names:	transferrin
NCBI Official Symbol:	Tf
NCBI Official Synonym Symbols:	Tfn; Trf
NCBI Protein Information:	serotransferrin
UniProt Protein Name:	Serotransferrin
UniProt Synonym Protein Names:	Beta-1 metal-binding globulin; Liver regeneration-related protein LRRG03; Siderophilin
UniProt Gene Name:	Tf