Description
Product Name: | TET3 Monoclonal Antibody |
Product Code: | CAB21930 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC52663 |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:2000-1:20000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | Neuro-2a |
Cellular Location: | cytoplasm, female pronucleus, male pronucleus, nucleoplasm, nucleus |
Enables methylcytosine dioxygenase activity. Involved in DNA demethylation of male pronucleus. Acts upstream of or within DNA demethylation. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including central nervous system; early conceptus; future brain; and genitourinary system. Orthologous to human TET3 (tet methylcytosine dioxygenase 3).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of mouse TET3 (Q8BG87). |
Sequence: | MSQFQ VPLAV QPDLS GLYDF PQGQV MVGGF QGPGL PMAGS ETQLR GGGDG RKKRK RCGTC DPCRR LENCG SCTSC TNRRT HQICK LRKCE VLKKK AGLLK EVEIN AREGT GPWAQ GATVK TGSEL SPVDG PVPGQ MDSGP VYHGD SRQLS TSGAP VNGAR EPAGP GLLGA AGPWR VDQKP DWEAA SGPTH AARLE DAHDL VAFSA VAEAV SSYGA LSTRL YETFN REMSR EAGSN GRGPR PESCS EGSED LDTLQ TALAL ARHGM KPPNC TCDGP ECPDF LEWLE |
Synonyms: | B430006D22Rik, D230004J03Rik |
Calculated MW: | 195kDa |
Observed MW: | 230kDa |