Description
| Product Name: | TET1 Monoclonal Antibody |
| Product Code: | CAB23162 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59030 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Hep G2, Mouse brain |
| Cellular Location: | Nucleus |
| Customer Validation: | WB(Mus musculus) |
DNA methylation is an epigenetic mechanism that is important for controlling gene expression. The protein encoded by this gene is a demethylase that belongs to the TET (ten-eleven translocation) family. Members of the TET protein family play a role in the DNA methylation process and gene activation.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1800-1900 of human TET (NP_085128.2). |
| Sequence: | TLGSN TETVQ PEVKS ETEPH FILKS SDNTK TYSLM PSAPH PVKEA SPGFS WSPKT ASATP APLKN DATAS CGFSE RSSTP HCTMP SGRLS GANAA AADGP G |
| Synonyms: | LCX, CXXC6, bA119F7.1 |
| Calculated MW: | 235kDa |
| Observed MW: | 310kDa |