TET1 Monoclonal Antibody (CAB21914)
- SKU:
- CAB21914
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | TET1 Monoclonal Antibody |
| Product Code: | CAB21914 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51468 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | ESCS |
| Cellular Location: | nucleoplasm, nucleus |
Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1749-1902 of mouse TET1 (NP_001240786.1). |
| Sequence: | HNTKS FSSAS STSHL VKDES TDFCP LQASS AETST CTYSK TASGG FAETS SILHC TMPSG AHSGA NAAAG ECTGT VQPAE VAAHP HQSLP TADSP VHAEP LTSPS EQLTS NQSNQ QLPLL SNSQK LASCQ VEDER HPEAD EPQHP EDDNL PQLD |
| Synonyms: | LCX, Cxxc6, mKIAA1676, D10Ertd17e, 2510010B09Rik |
| Calculated MW: | 219kDa |
| Observed MW: | 260kDa |
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