TECTB Antibody (PACO61129)
- SKU:
- PACO61129
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TECTB Antibody (PACO61129) |
| Antibody SKU: | PACO61129 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Beta-tectorin protein (18-118AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO61129 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals. |
| Synonyms: | Beta-tectorin, TECTB |
| UniProt Protein Function: | TECTB: One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.Protein type: Membrane protein, GPI anchorChromosomal Location of Human Ortholog: 10q25.2Cellular Component: extracellular region; plasma membrane; proteinaceous extracellular matrixMolecular Function: extracellular matrix structural constituentBiological Process: C-terminal protein lipidation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q96PL2 |
| NCBI GenInfo Identifier: | 17158035 |
| NCBI Gene ID: | 6975 |
| NCBI Accession: | NP_478129.1 |
| UniProt Secondary Accession: | Q96PL2,Q5VW53 |
| UniProt Related Accession: | Q96PL2 |
| Molecular Weight: | 36,956 Da |
| NCBI Full Name: | beta-tectorin |
| NCBI Synonym Full Names: | tectorin beta |
| NCBI Official Symbol: | TECTB |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | beta-tectorin |
| UniProt Protein Name: | Beta-tectorin |
| UniProt Synonym Protein Names: | |
| Protein Family: | Beta-tectorin |
| UniProt Gene Name: | TECTB |
| UniProt Entry Name: |
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