Tec Monoclonal Antibody
- SKU:
- CAB22074
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Tec Monoclonal Antibody |
| Product Code: | CAB22074 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53949 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:10000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, Mouse liver, Mouse kidney, Rat liver, MCF7 |
| Cellular Location: | Cell membrane, Cytoplasm, Peripheral membrane protein, cytoskeleton |
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Tec (NP_003206.2). |
| Sequence: | MNFNT ILEEI LIKRS QQKKK TSPLN YKERL FVLTK SMLTY YEGRA EKKYR KGFID VSKIK CVEIV KNDDG VIPCQ NKYPF QVVHD ANTLY IFAPS PQSRD LWVKK LKEEI KNNNN IMIKY HPKFW TDGSY QCCRQ TEKLA PGCEK YNLFE SSIRK ALPPA PETKK RRPPP PIPLE EEDNS EEIVV AMYDF QAAEG HDLRL ERGQE YLILE KNDVH WWRAR DKYGN EGYIP SNYVT GKKSN NLDQY EWYCR NMNRS KAEQL LRSED KEGGF MVRDS SQPGL |
| Synonyms: | PSCTK4 |
| Calculated MW: | 74kDa |
| Observed MW: | 73kDa |
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