TCIRG1 Monoclonal Antibody
- SKU:
- CAB24945
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | TCIRG1 Monoclonal Antibody |
| Product Code: | CAB24945 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64630 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:100-1:500, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse spleen |
| Cellular Location: | Membrane, Multi-pass membrane protein |
This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to aminoacids 1-356 of human TCIRG1(NP_006010.2). |
| Sequence: | MGSMF RSEEV ALVQL FLPTA AAYTC VSRLG ELGLV EFRDL NASVS AFQRR FVVDV RRCEE LEKTF TFLQE EVRRA GLVLP PPKGR LPAPP PRDLL RIQEE TERLA QELRD VRGNQ QALRA QLHQL QLHAA VLRQG HEPQL AAAHT DGASE RTPLL QAPGG PHQDL RVNFV AGAVE PHKAP ALERL LWRAC RGFLI ASFRE LEQPL EHPVT GEPAT WMTFL ISYWG EQIGQ KIRKI TDCFH CHVFP FLQQE EARLG ALQQL QQQSQ ELQEV LGETE RFLSQ VLGRV LQLLP PGQVQ VHKMK AVYLA LNQCS VSTTH KCLIA EAWCS VRDLP ALQEA LRDSS MEEGV SAVAH RIPCR D |
| Synonyms: | a3, Stv1, Vph1, Atp6i, OC116, OPTB1, TIRC7, ATP6N1C, ATP6V0A3, OC-116kDa |
| Calculated MW: | 93kDa |
| Observed MW: | 116kDa |
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