TCF7L1 Polyclonal Antibody
- SKU:
- CAB9006
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | TCF7L1 Polyclonal Antibody |
| Product Code: | CAB9006 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, HCT116, A-549, A-431, Mouse lung, Mouse brain, Mouse skin, Rat lung, Rat skin |
| Cellular Location: | Nucleus |
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 260-340 of human TCF7L1 (NP_112573.1). |
| Sequence: | YSLPP GGFRH PYPAL AMNAS MSSLV SSRFS PHMVA PAHPG LPTSG IPHPA IVSPI VKQEP APPSL SPAVS VKSPV TVKKE E |
| Synonyms: | TCF3, TCF-3 |
| Calculated MW: | 63kDa |
| Observed MW: | 75kDa |
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