TCEB3C Antibody (PACO02565)
- SKU:
- PACO02565
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TCEB3C Antibody |
| Antibody SKU: | PACO02565 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Elongin A3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | TCEB3C; TCEB3L2; RNA polymerase II transcription factor SIII subunit A3; Elongin-A3; EloA3; Transcription elongation factor B polypeptide 3C |
| UniProt Protein Function: | TCEB3C: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).Chromosomal Location of Human Ortholog: 18q21.1Cellular Component: integral to membrane; nucleusMolecular Function: DNA bindingBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | The SIII (or elongin) transcription elongation factor complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. This complex is a heterotrimer, composed of the transcriptionally active subunit A, A2 or A3 (or elongin A, A2 or A3) and two regulatory subunits, B and C (or elongin B and C). This gene encodes subunit A3. A3 and A are ubiquitously expressed, whereas A2 is specifically expressed in the testis. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q8NG57 |
| NCBI GenInfo Identifier: | 156938279 |
| NCBI Gene ID: | 162699 |
| NCBI Accession: | NP_663628.2 |
| UniProt Secondary Accession: | Q8NG57 |
| UniProt Related Accession: | Q8NG57 |
| Molecular Weight: | |
| NCBI Full Name: | elongin-A3 |
| NCBI Synonym Full Names: | elongin A3 |
| NCBI Official Symbol: | ELOA3 |
| NCBI Official Synonym Symbols: | ELOA3A; HsT829; TCEB3C; TCEB3L2 |
| NCBI Protein Information: | elongin-A3 |
| UniProt Protein Name: | RNA polymerase II transcription factor SIII subunit A3 |
| UniProt Synonym Protein Names: | Elongin-A3; EloA3; Transcription elongation factor B polypeptide 3C |
| Protein Family: | Elongation factor |
| UniProt Gene Name: | TCEB3C |
| UniProt Entry Name: | ELOA3_HUMAN |
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