Description
Antibody Name: | TCEB3B/TCEB3C Antibody |
Antibody SKU: | PACO04524 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IF |
Recommended Dilutions: | IF:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | synthesized peptide derived from the Internal region of human Elongin A2/3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | TCEB3B; TCEB3L; RNA polymerase II transcription factor SIII subunit A2; Elongin-A2; EloA2; Transcription elongation factor B polypeptide 3B; TCEB3C; TCEB3L2; RNA polymerase II transcription factor SIII subunit A3; Elongin-A3; EloA3; Transcr |
UniProt Protein Function: | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). |
NCBI Summary: | This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IYF1 |
NCBI GenInfo Identifier: | 45439357 |
NCBI Gene ID: | 51224 |
NCBI Accession: | NP_057511.2 |
UniProt Secondary Accession: | Q8IYF1,Q9P2V9, |
UniProt Related Accession: | Q8IYF1 |
Molecular Weight: | 83 kDa |
NCBI Full Name: | elongin-A2 |
NCBI Synonym Full Names: | elongin A2 |
NCBI Official Symbol: | ELOA2 |
NCBI Official Synonym Symbols: | HsT832; TCEB3B; TCEB3L |
NCBI Protein Information: | elongin-A2 |
UniProt Protein Name: | Elongin-A2 |
UniProt Synonym Protein Names: | RNA polymerase II transcription factor SIII subunit A2; Transcription elongation factor B polypeptide 3B |
UniProt Gene Name: | ELOA2 |