Description
| Antibody Name: | TBX18/TBX15 Antibody |
| Antibody SKU: | PACO01591 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the Internal region of human TBX15/18. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | TBX18; T-box transcription factor TBX18; T-box protein 18; TBX15; TBX14; T-box transcription factor TBX15; T-box protein 15; T-box transcription factor TBX14; T-box protein 14 |
| UniProt Protein Function: | TBX18: Probable transcriptional regulator involved in developmental processes. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 6q14-q15 Cellular Component: nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent Disease: Huntington Disease |
| NCBI Summary: | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
| UniProt Code: | O95935 |
| NCBI GenInfo Identifier: | 122937456 |
| NCBI Gene ID: | 9096 |
| NCBI Accession: | NP_001073977.1 |
| UniProt Secondary Accession: | O95935,Q7Z6U4, Q9UJI6, A2RU13, |
| UniProt Related Accession: | O95935 |
| Molecular Weight: | 80.8 kDa |
| NCBI Full Name: | T-box transcription factor TBX18 |
| NCBI Synonym Full Names: | T-box 18 |
| NCBI Official Symbol: | TBX18Â Â |
| NCBI Protein Information: | T-box transcription factor TBX18 |
| UniProt Protein Name: | T-box transcription factor TBX18 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | TBX18Â Â |
| UniProt Entry Name: | TBX18_HUMAN |
