TBX18 Antibody (PACO30298)
- SKU:
- PACO30298
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TBX18 Antibody (PACO30298) |
| Antibody SKU: | PACO30298 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human T-box transcription factor TBX18 protein (1-607AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Probable transcriptional regulator involved in developmental processes. |
| Synonyms: | T-box transcription factor TBX18 (T-box protein 18), TBX18 |
| UniProt Protein Function: | TBX18: Probable transcriptional regulator involved in developmental processes. |
| UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 6q14-q15 Cellular Component: nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent Disease: Huntington Disease |
| NCBI Summary: | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
| UniProt Code: | O95935 |
| NCBI GenInfo Identifier: | 122937456 |
| NCBI Gene ID: | 9096 |
| NCBI Accession: | NP_001073977.1 |
| UniProt Secondary Accession: | O95935,Q7Z6U4, Q9UJI6, A2RU13, |
| UniProt Related Accession: | O95935 |
| Molecular Weight: | 80.8 kDa |
| NCBI Full Name: | T-box transcription factor TBX18 |
| NCBI Synonym Full Names: | T-box 18 |
| NCBI Official Symbol: | TBX18 |
| NCBI Protein Information: | T-box transcription factor TBX18 |
| UniProt Protein Name: | T-box transcription factor TBX18 |
| Protein Family: | T-box transcription factor |
| UniProt Gene Name: | TBX18 |
| UniProt Entry Name: | TBX18_HUMAN |
