Description
Antibody Name: | TBX18 Antibody (PACO22644) |
Antibody SKU: | PACO22644 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human TBX18. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from Jurkat cells, using TBX18 antibody. |
Background: | Probable transcriptional regulator involved in developmental processes. |
Synonyms: | T-box protein 18; T-box transcription factor TBX18; TBX18; |
UniProt Protein Function: | TBX18: Probable transcriptional regulator involved in developmental processes. |
UniProt Protein Details: | Protein type:Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 6q14-q15 Cellular Component: nucleus Molecular Function:protein binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activity Biological Process: anterior/posterior axis specification; morphogenesis of embryonic epithelium; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell-cell adhesion; positive regulation of epithelial cell proliferation; sensory perception of sound; smooth muscle cell differentiation; somitogenesis; transcription, DNA-dependent Disease: Huntington Disease |
NCBI Summary: | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
UniProt Code: | O95935 |
NCBI GenInfo Identifier: | 122937456 |
NCBI Gene ID: | 9096 |
NCBI Accession: | NP_001073977.1 |
UniProt Secondary Accession: | O95935,Q7Z6U4, Q9UJI6, A2RU13, |
UniProt Related Accession: | O95935 |
Molecular Weight: | 80.8 kDa |
NCBI Full Name: | T-box transcription factor TBX18 |
NCBI Synonym Full Names: | T-box 18 |
NCBI Official Symbol: | TBX18 |
NCBI Protein Information: | T-box transcription factor TBX18 |
UniProt Protein Name: | T-box transcription factor TBX18 |
Protein Family: | T-box transcription factor |
UniProt Gene Name: | TBX18 |
UniProt Entry Name: | TBX18_HUMAN |
Antibodies | ELISA Kits |
TBX18 Antibody (PACO05688) | TBX18 Transcription Factor Activity Assay |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |