Name: Tbx15 Antibody (PACO30294)
SKU: PACO30294
Availability: OutOfStock

Antibody Name:	Tbx15 Antibody (PACO30294)
Antibody SKU:	PACO30294
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse T-box transcription factor TBX15 protein (1-120AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes.
Synonyms:	T-box transcription factor TBX15 (T-box protein 15) (MmTBx8) (T-box transcription factor TBX14) (T-box protein 14), Tbx15, Tbx14 Tbx8

UniProt Protein Function:	TBX15: Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes. Defects in TBX15 are the cause of Cousin syndrome (COUSS); also known as craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature. Cousin syndrome is defined as pelviscapular dysplasia with epiphyseal abnormalities, congenital dwarfism and facial dysmorphy (frontal bossing, hypertelorism, narrow palpebral fissures, deep set globes, strabismus, low-set posteriory rotated and unusually formed external ears, dysplasia of conchae, small chin, short neck with redundant skin folds, and a low hairline). Intelligence may vary from normal to moderately impaired. Radiographic features comprise aplasia of the body of the scapula, hypoplasia of the iliac bone, humeroradial synosthosis, dislocation of the femoral heads, and moderate brachydactyly. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-bindingCellular Component: nucleusMolecular Function: DNA binding; protein heterodimerization activity; protein homodimerization activity; transcription factor activityBiological Process: embryonic cranial skeleton morphogenesis; embryonic skeletal morphogenesis; regulation of transcription, DNA-dependent; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:
UniProt Code:	O70306
NCBI GenInfo Identifier:	124286802
NCBI Gene ID:	21384
NCBI Accession:	NP_033349.2
UniProt Secondary Accession:	O70306,O54840, Q5GBG1
UniProt Related Accession:	O70306
Molecular Weight:	65,802 Da
NCBI Full Name:	T-box transcription factor TBX15
NCBI Synonym Full Names:	T-box 15
NCBI Official Symbol:	Tbx15
NCBI Official Synonym Symbols:	de; Tbx8; Tbx14
NCBI Protein Information:	T-box transcription factor TBX15
UniProt Protein Name:	T-box transcription factor TBX15
UniProt Synonym Protein Names:	MmTBx8; T-box transcription factor TBX14; T-box protein 14
Protein Family:	T-box transcription factor
UniProt Gene Name:	Tbx15
UniProt Entry Name:	TBX15_MOUSE