TBL1Y Antibody (PACO17368)
- SKU:
- PACO17368
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TBL1Y Antibody (PACO17368) |
| Antibody SKU: | PACO17368 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human TBL1Y |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17368(TBL1Y Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO17368(TBL1Y Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. |
| Synonyms: | transducin (beta)-like 1, Y-linked |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BQ87 |
| NCBI GenInfo Identifier: | 15150805 |
| NCBI Gene ID: | 90665 |
| NCBI Accession: | NP_150600 |
| UniProt Secondary Accession: | Q9BQ87 |
| UniProt Related Accession: | Q9BQ87 |
| Molecular Weight: | 57kDa |
| NCBI Full Name: | F-box-like/WD repeat-containing protein TBL1Y |
| NCBI Synonym Full Names: | transducin beta like 1 Y-linked |
| NCBI Official Symbol: | TBL1Y |
| NCBI Official Synonym Symbols: | TBL1 |
| NCBI Protein Information: | F-box-like/WD repeat-containing protein TBL1Y |
| UniProt Protein Name: | F-box-like/WD repeat-containing protein TBL1Y |
| UniProt Synonym Protein Names: | Transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked |
| Protein Family: | F-box-like/WD repeat-containing protein |
| UniProt Gene Name: | TBL1Y |
| UniProt Entry Name: | TBL1Y_HUMAN |
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