TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)
![TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58765/63947/tbca-monoclonal-antibody-pat1a5at-cpab0544__05759__54493.1706535210.jpg?c=1 "TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)")
- SKU:
- CPAB0544
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT1A5AT
- Applications:
- WB
- Applications:
- ELISA
![TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58765/63947/tbca-monoclonal-antibody-pat1a5at-cpab0544__05759__54493.1706535210.jpg?c=1&imbypass=on "TBCA Monoclonal Antibody [PAT1A5AT] (CPAB0544)")
Description
system_update_alt Datasheet
| Product Name: | TBCA Antibody |
| Product Sku: | CPAB0544 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human TBCA mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TBCA amino acids 1-18 purified from Ecoli. |
| Clone: | PAT1A5AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | TBCA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins (cofactors A, D, E, and C) implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability, if reduced it causes a decrease in the amount of soluble tubulin, alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex, afterward, interaction with cofactor C triggers the release of tubulin polypeptides that are committed to the native state. |
| Synonyms: | Tubulin-specific chaperone A, Tubulin-folding cofactor A, CFA, TCP1-chaperonin cofactor A, TBCA. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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