TBC1D25 Antibody (PACO62759)
- SKU:
- PACO62759
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TBC1D25 Antibody (PACO62759) |
| Antibody SKU: | PACO62759 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human TBC1 domain family member 25 protein (1-219AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO62759 diluted at 1:400 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO62759 diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes. |
| Synonyms: | TBC1 domain family member 25, TBC1D25, OATL1 |
| UniProt Protein Function: | TBC1D25: Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Vesicle; GAPs; GAPs, RabChromosomal Location of Human Ortholog: Xp11.23Cellular Component: autophagic vacuole; cytoplasmic vesicleMolecular Function: protein bindingBiological Process: autophagy |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein with a TBC domain and may function as a Rab GTPase activating protein. This gene was previously known as ornithine aminotransferase-like 1, but has no similarity to ornithine aminotransferase. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q3MII6 |
| NCBI GenInfo Identifier: | 19684189 |
| NCBI Gene ID: | 4943 |
| NCBI Accession: | AAH26050.1 |
| UniProt Secondary Accession: | Q3MII6,Q08AN9, Q3MII4, Q8TAR9 |
| UniProt Related Accession: | Q3MII6 |
| Molecular Weight: | 76 kDa (MW of target protein) |
| NCBI Full Name: | TBC1D25 protein, partial |
| NCBI Synonym Full Names: | TBC1 domain family, member 25 |
| NCBI Official Symbol: | TBC1D25 |
| NCBI Official Synonym Symbols: | MG81; OATL1 |
| NCBI Protein Information: | TBC1 domain family member 25 |
| UniProt Protein Name: | TBC1 domain family member 25 |
| UniProt Synonym Protein Names: | |
| Protein Family: | TBC1 domain family |
| UniProt Gene Name: | TBC1D25 |
| UniProt Entry Name: | TBC25_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli
PCDHA8 Antibody
Overview Product Name:PCDHA8 AntibodyProduct Code:PACO64893Size:50µLTarget Names:PCDHA8Species Reactivity:HumanH