Tau Monoclonal Antibody
- SKU:
- CAB23490
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
Description
| Product Name: | Tau Monoclonal Antibody |
| Product Code: | CAB23490 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58125 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, IP, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | SH-SY5Y, U-251MG, Mouse brain, Rat brain |
| Cellular Location: | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, axon, Cytoskeleton, Cytosol |
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAPT (NM_005910.6) |
| Sequence: | MAEPR QEFEV MEDHA GTYGL GDRKD QGGYT MHQDQ EGDTD AGLKE SPLQT PTEDG SEEPG SETSD AKSTP TAEDV TAPLV DEGAP GKQAA AQPHT EIPEG |
| Synonyms: | TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103, Tau-PHF6 |
| Calculated MW: | 79kDa |
| Observed MW: | 50-80kDa |
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