TAS2R5 Antibody (PACO64539)
- SKU:
- PACO64539
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TAS2R5 Antibody (PACO64539) |
| Antibody SKU: | PACO64539 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Taste receptor type 2 member 5 protein (149-164AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Antigen Affinity purified & Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO64539 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate α gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Synonyms: | Taste receptor type 2 member 5 (T2R5), TAS2R5 |
| UniProt Protein Function: | TAS2R5: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, T2R familyChromosomal Location of Human Ortholog: 7q31.3-q32Cellular Component: plasma membrane; integral to membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of taste; chemosensory behavior; detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NYW4 |
| NCBI GenInfo Identifier: | 9507173 |
| NCBI Gene ID: | 54429 |
| NCBI Accession: | NP_061853.1 |
| UniProt Secondary Accession: | Q9NYW4 |
| UniProt Related Accession: | Q9NYW4 |
| Molecular Weight: | |
| NCBI Full Name: | taste receptor type 2 member 5 |
| NCBI Synonym Full Names: | taste 2 receptor member 5 |
| NCBI Official Symbol: | TAS2R5 |
| NCBI Official Synonym Symbols: | T2R5 |
| NCBI Protein Information: | taste receptor type 2 member 5 |
| UniProt Protein Name: | Taste receptor type 2 member 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | TAS2R5 |
| UniProt Entry Name: | TA2R5_HUMAN |
| Antibodies |
| TAS2R5 Antibody (PACO04639) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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