TAS2R41 Antibody (PACO30270)
- SKU:
- PACO30270
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TAS2R41 Antibody (PACO30270) |
| Antibody SKU: | PACO30270 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Taste receptor type 2 member 41 protein (205-234AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of MCF-7 cells using PACO30270 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO30270 at dilution of 1:100. |
| Background: | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate α gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
| Synonyms: | Taste receptor type 2 member 41 (T2R41) (Taste receptor type 2 member 59) (T2R59), TAS2R41 |
| UniProt Protein Function: | TAS2R41: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 7q35Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P59536 |
| NCBI GenInfo Identifier: | 261260079 |
| NCBI Gene ID: | 259287 |
| NCBI Accession: | P59536.2 |
| UniProt Secondary Accession: | P59536,P59550, Q495I2, Q50KJ5, Q50KJ6, Q50KJ7, Q645W7 |
| UniProt Related Accession: | P59536 |
| Molecular Weight: | 35,896 Da |
| NCBI Full Name: | Taste receptor type 2 member 41 |
| NCBI Synonym Full Names: | taste 2 receptor member 41 |
| NCBI Official Symbol: | TAS2R41 |
| NCBI Official Synonym Symbols: | T2R41; T2R59 |
| NCBI Protein Information: | taste receptor type 2 member 41 |
| UniProt Protein Name: | Taste receptor type 2 member 41 |
| UniProt Synonym Protein Names: | Taste receptor type 2 member 59; T2R59 |
| Protein Family: | Taste receptor |
| UniProt Gene Name: | TAS2R41 |
| UniProt Entry Name: | T2R41_HUMAN |
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