TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)
![TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58775/63957/tardbp-monoclonal-antibody-pk1b8at-cpab0554__65447__96005.1706535213.jpg?c=1 "TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)")
- SKU:
- CPAB0554
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- Pk1B8AT
- Applications:
- WB
- Applications:
- ELISA
- Applications:
- IHC
![TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58775/63957/tardbp-monoclonal-antibody-pk1b8at-cpab0554__65447__96005.1706535213.jpg?c=1&imbypass=on "TARDBP Monoclonal Antibody [Pk1B8AT] (CPAB0554)")
Description
system_update_alt Datasheet
| Product Name: | TARDBP Antibody |
| Product Sku: | CPAB0554 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human TARDBP mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TARDBP amino acids 1-26 purified from Ecoli. |
| Clone: | Pk1B8AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA, Immunohistochemistry |
| Purification Method: | TARDBP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG1 |
| Background: | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome which produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
| Synonyms: | TAR DNA-binding protein 43, TDP-43, TARDBP, TDP43, ALS10. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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