TAGAP Antibody (PACO37910)
- SKU:
- PACO37910
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TAGAP Antibody (PACO37910) |
| Antibody SKU: | PACO37910 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human T-cell activation Rho GTPase-activating protein (97-260AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO37910 at dilution of 1:100. |
| Background: | May function as a GTPase-activating protein and may play important roles during T-cell activation. |
| Synonyms: | T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein), TAGAP, TAGAP1 |
| UniProt Protein Function: | TAGAP: an apparent GTPase-activating protein (GAP) for Rho monomeric G proteins. May play important roles during T-cell activation. Mutations have been associated with various autoimmune conditions including rheumatoid arthritis, Crohn¿s disease, and celiac disease. Four isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; GAPsChromosomal Location of Human Ortholog: 6q25.3Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q8N103 |
| NCBI GenInfo Identifier: | 74750874 |
| NCBI Gene ID: | 117289 |
| NCBI Accession: | Q8N103.1 |
| UniProt Secondary Accession: | Q8N103,Q2NKM8, Q8NI40, Q96KZ2, Q96QA2 |
| UniProt Related Accession: | Q8N103 |
| Molecular Weight: | 29,977 Da |
| NCBI Full Name: | T-cell activation Rho GTPase-activating protein |
| NCBI Synonym Full Names: | T-cell activation RhoGTPase activating protein |
| NCBI Official Symbol: | TAGAP |
| NCBI Official Synonym Symbols: | FKSG15; IDDM21; TAGAP1; ARHGAP47 |
| NCBI Protein Information: | T-cell activation Rho GTPase-activating protein |
| UniProt Protein Name: | T-cell activation Rho GTPase-activating protein |
| UniProt Synonym Protein Names: | T-cell activation GTPase-activating protein |
| Protein Family: | T-cell activation Rho GTPase-activating protein |
| UniProt Gene Name: | TAGAP |
| UniProt Entry Name: | TAGAP_HUMAN |
| Antibodies |
| TAGAP Antibody (PACO03408) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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