TAF1A Antibody (PACO52306)
- SKU:
- PACO52306
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | TAF1A Antibody (PACO52306) |
| Antibody SKU: | PACO52306 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human TATA box-binding protein-associated factor RNA polymerase I subunit A protein (251-325AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO52306 at dilution of 1:100. |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate, HEK293 whole cell lysate, PC-3 whole cell lysate. All lanes: TAF1A antibody at 2.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53, 40 kDa. Observed band size: 53, 40 kDa. |
| Background: | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. |
| Synonyms: | TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A), TAF1A |
| UniProt Protein Function: | TAF1A: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q42 Cellular Component: intracellular membrane-bound organelle; microtubule cytoskeleton; nucleoplasm; nucleus; RNA polymerase I transcription factor complex Molecular Function:protein binding Biological Process: positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase I promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter |
| NCBI Summary: | This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011] |
| UniProt Code: | Q15573 |
| NCBI GenInfo Identifier: | 74739864 |
| NCBI Gene ID: | 9015 |
| NCBI Accession: | Q15573.1 |
| UniProt Secondary Accession: | Q15573,Q9NWA1, B2RDZ8, D3DTB7, |
| UniProt Related Accession: | Q15573 |
| Molecular Weight: | 39,615 Da |
| NCBI Full Name: | TATA box-binding protein-associated factor RNA polymerase I subunit A |
| NCBI Synonym Full Names: | TATA-box binding protein associated factor, RNA polymerase I subunit A |
| NCBI Official Symbol: | TAF1A |
| NCBI Official Synonym Symbols: | SL1; RAFI48; TAFI48; MGC:17061 |
| NCBI Protein Information: | TATA box-binding protein-associated factor RNA polymerase I subunit A |
| UniProt Protein Name: | TATA box-binding protein-associated factor RNA polymerase I subunit A |
| UniProt Synonym Protein Names: | RNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1; Transcription initiation factor SL1/TIF-IB subunit A |
| Protein Family: | TATA box-binding protein-associated factor |
| UniProt Gene Name: | TAF1A |
| UniProt Entry Name: | TAF1A_HUMAN |
| Antibodies | ELISA Kits |
| TAF1A Antibody (PACO05664) | TAF1A Colorimetric Cell-Based ELISA |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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