Description
| Antibody Name: | TADA2B Antibody (PACO37230) |
| Antibody SKU: | PACO37230 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transcriptional adapter 2-β protein (29-328AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO37230 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human skin tissue using PACO37230 at dilution of 1:100. |
| Background: | Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2. |
| Synonyms: | Transcriptional adapter 2-β (ADA2-like protein beta) (ADA2-beta), TADA2B, ADA2B |
| UniProt Protein Function: | TADA2B: Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 4p16.1 Molecular Function:chromatin binding; histone acetyltransferase activity; transcription coactivator activity; transcription factor activity Biological Process: chromatin remodeling; positive regulation of histone acetylation; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | TADA2B functions as a transcriptional adaptor protein that potentiates transcription through coordination of histone acetyltransferase (HAT) activity and by linking activation factors to basal transcriptional machinery (Barlev et al., 2003 [PubMed 12972612]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q86TJ2 |
| NCBI GenInfo Identifier: | 166225686 |
| NCBI Gene ID: | 93624 |
| NCBI Accession: | Q86TJ2.2 |
| UniProt Related Accession: | Q86TJ2 |
| Molecular Weight: | 37kDa; 39kDa; 48kDa |
| NCBI Full Name: | Transcriptional adapter 2-beta |
| NCBI Synonym Full Names: | transcriptional adaptor 2B |
| NCBI Official Symbol: | TADA2B |
| NCBI Official Synonym Symbols: | ADA2B; ADA2(beta) |
| NCBI Protein Information: | transcriptional adapter 2-beta |
| UniProt Protein Name: | Transcriptional adapter 2-beta |
| UniProt Synonym Protein Names: | ADA2-like protein beta; ADA2-beta |
| Protein Family: | Transcriptional adapter |
| UniProt Gene Name: | TADA2B |
| Antibodies |
| Anti-TADA2B Antibody (CAB13749) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |

