SYTL5 Antibody (PACO17183)
- SKU:
- PACO17183
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SYTL5 Antibody (PACO17183) |
| Antibody SKU: | PACO17183 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human SYTL5 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17183(SYTL5 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO17183(SYTL5 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. |
| Synonyms: | synaptotagmin-like 5 |
| UniProt Protein Function: | SYTL5: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: Xp21.1Cellular Component: plasma membraneMolecular Function: calcium ion binding; calcium-dependent phospholipid binding; clathrin binding; protein binding; syntaxin bindingBiological Process: calcium ion-dependent exocytosis of neurotransmitter; regulation of calcium ion-dependent exocytosis; vesicle fusion |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to the synaptotagmin-like (Slp) protein family, which contains a unique homology domain at the N-terminus, referred to as the Slp homology domain (SHD). The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of this gene is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
| UniProt Code: | Q8TDW5 |
| NCBI GenInfo Identifier: | 124297060 |
| NCBI Gene ID: | 94122 |
| NCBI Accession: | BC131585 |
| UniProt Secondary Accession: | Q8TDW5,A2RRF2 |
| UniProt Related Accession: | Q8TDW5 |
| Molecular Weight: | 83,918 Da |
| NCBI Full Name: | Homo sapiens synaptotagmin-like 5, mRNA |
| NCBI Synonym Full Names: | synaptotagmin like 5 |
| NCBI Official Symbol: | SYTL5 |
| NCBI Official Synonym Symbols: | slp5 |
| NCBI Protein Information: | synaptotagmin-like protein 5 |
| UniProt Protein Name: | Synaptotagmin-like protein 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Synaptotagmin-like protein |
| UniProt Gene Name: | SYTL5 |
| UniProt Entry Name: | SYTL5_HUMAN |
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